Leukemia

Causes of leukemia are not yet fully elucidated. Cytogenetic and molecular techniques in the new developments, genetic predisposition, radiation, benzene and its derivatives (glue, etc..), Pesticides such as chemicals, some hereditary diseases and some viral diseases together, causing leukemia that studies have shown. Leukemia is seen in every age. Most frequently in childhood is increasing in 2-5 years. One under the age of 10 years of age on the response to treatment in the new cases is decreasing.
Any effect of circulating blood in our veins is essential in making our home in cells of bone marrow blasts with a password change is not what we call mature blood cells occurs in growth. These cells spread rapidly to the bone marrow, lymph glands, spleen, liver, brain and central nervous system are kept.

Symptoms:
The symptoms of leukemia in children:

* Loss of appetite
* Anemia
* Weight Loss
* Bone pain in the legs
* Bleeding under the skin (red spots or bruising)
* Nose bleeding and gum
* Fire

bulgulardır.Ayrıca first observed the symptoms spread to organs, such as headache, vomiting, abdominal pain, visual disturbances may importance. Their children to apply these complaints hematology (blood disorders), experts in the examination, mainly the liver and spleen enlargement, enlarged lymph glands, bleeding manifestations can be detected.

Blood, bone marrow cells and genetic tests to determine the type of results can be diagnosed.

The diagnostic tests are usually more of this type of leukemia, will aid in determining treatment principles.

TREATMENT:

Treatment primarily starts with an overview of the correction methods. In this phase of blood or blood in the special cell of the donors (voluntary blood donors persons) taking leukemias be given to the infection exists, the necessary struggle to make, kidneys, liver and heart of the chemotherapy drugs side effects of protection measures to be taken is very important.

In addition, patients and families are informed about the disease, leukemia is not hopeless, in contrast with a good moral support leukemia treatment and up to rise up to 85% healing rate is classified as second-line therapy is disclosed.

FIRST PRINCIPLES TREATMENT and TREATMENT:

Very high doses, for at least six different types of intravenous and oral medications should be given within 4-6 weeks. The aim of the blast, called a malignant parent cell is destroyed.

However, these chemotherapy drugs, unfortunately, does not affect only the bad cells, our body is good, useful cells are destroyed. Therefore, our children are balding, their mouths, gaping wounds in his intestine, behave sluggish. Again, the defense cells to protect our body against infections and immune system was also destroyed by drugs are destroyed, the smallest microbe, disease agents spread all over the body, even with severe febrile infection is caused.

Therefore, the people around our children with leukemia, the air, water, wear a mask to protect against microbes and are not taken.

Treatment Methods
The basic principles for the treatment of leukemia in the bone marrow of password changes that occur in the main blood cells mature and non-proliferation of cells, called blasts, and after stopping to ensure normal blood elements.

Malignant blast cells reproduce very quickly. According to the various stages of maturity and reproduce when they are divided into: 1) mitosis, 2) G circuit, 3) S is a circuit. The aim of the treatment, effects of different drugs within the framework of a program using a long time is to kill all stages in the blasts.

Approximately 3 years of treatment takes place in four stages:

1 - INSTALLING THE TREATMENT (Operation Sledgehammer)
5-6 different types of intravenous drugs are given simultaneously. The aim of malignant cells is to die quickly in two months. We have invaded the body of friendly forces against enemy forces gather, rifle, is attacked with grenades. Nearly started a war of independence.

2 - Treatment of reinforcement (Influence of Jet)
Panicky, break the bad cells immediately to protect themselves, to resist is wrapped in armor, hiding and are trying to replicate. Our armed forces, friendly forces of the body with air, land and sea is attacked by enemy bombs. This treatment takes 3-4 months at very high doses of intravenous drugs are given different effective.

Unfortunately that's the secret to dying cells in our body benefit, the hair is shed, comes in mouth sores.

3 - preventive treatment (Intelligence):
Bone marrow was defeated, shattered, scattered the enemy cells of our brain and nervous system and reproductive organs in place, to prowl through the activities of the preventive treatment. In some cases, radiotherapy (radiation treatment) may be applied. They functioned as a kind of secret service.

4 - Non-Permanence TREATMENT AGAIN ALLOW be ORGANIZATIONS:
The aim was no longer destroy enemy cells in our body in any way to prevent re-replication. Until recently no one has blast and fragmentation is provided. Continues until approximately 2.5-3 years.

CAN Repeater?
3-3.5 years up to rise up to 85% of the total rate of complete recovery at the end of the treatment is provided. Only observed after treatment with control children, siblings and friends all right shall pursue their lives as normal. Like all of us can be eaten disease in individuals at risk of leukemia, again, even if there are less. In this case, a similar treatment and / or bone marrow transplantation can be applied.

TREATMENT PROGRAMS:
Selected in the times at which chemotherapy drugs and what doses given lengthy to-be determined after the experiments and applications. The most valuable scientists from Turkey participated in this study, hematology journals, are available to be announced at the congress. Scientific institutions were created in the success or failure of the treatment being evaluated and monitored. The point of interruption, in national and international scientific board reviews of new drugs, new dosages or different methods are implemented.

Chemotherapy drugs:
Unfortunately all teavisine leukemia-specific drugs are being supplied from abroad. in transit not be compromised, in appropriate circumstances dilution of heat and light protection, the desired time and speed delivery and veins outside not miss such an extremely difficult and exacting work together should be.

COST:
The drugs used in treatment is extremely expensive. A box is around 100 million pounds. Hundreds of bottles of medicine are used. Catheters, kits, serum, blood products can be calculated if the treatment costs hundreds of billions of pounds are found.

CHILDREN AND FAMILY PROBLEMS of leukemia:
To stay away from school
Be discriminated by friends
Improvement of society, these children had no chance to think
Mask think that is because the disease is contagious
Children's inability to participate in social activities (cinema, theater, ...)
The obligation of children to stay away from foods they love
Blood can not find
Poverty
Want to accompany their children at the hospital where the family business as a result of their work too often get permission to put an end to

HEMOLOJİ-ONCOLOGY H1N1 vaccine and bone marrow TRANPLANTASYON PATIENTS AND TREATMENT FOR PROPOSALS
Currently supplied to our country-risk groups and the dose of the vaccine company Novartis for vaccine-related recommendations that are based on information at hand. Also prepared by Ministry of Health in accordance with H1N1 disease and prophylactic monitoring algorithm is designed.

Patient groups, and suggestions:
1.KİT for patients:
EBMT is offered by the implementation of the protocol is recommended.

2.Lösemi, for patients with lymphoma and solid tumors:
a.Halen intensive chemotherapy patients
Patients on maintenance therapy b.Halen
c.Halen ambulatory patients receiving chemotherapy
d.Halen cut chemotherapy, patients in the first year
immunosuppressive therapy for various reasons not e.Malignitesi fields (including corticosteroids)
All of the patients in this group, the vaccine is recommended;

* Novartis vaccine:
Be done immediately after the second dose of 0.5 ml is recommended four weeks.

* Glaxo vaccine
6ay 9 years: 0.25ml be done immediately after the second dose four weeks to make
1 0 years later: whether four weeks immediately after the second dose of 0.5 ml is recommended.

* Accompanying mother and if possible, all family members must be recommended to be vaccinated.

* After treatment of infections in febrile neutropenic patients are recommended to be vaccinated.
f. Currently, chemotherapy has been lost, more than a year past, such as patients with normal healthy children in schools is recommended to receive vaccination protocol.
Antiviral therapy applications:
Treatment
Showing signs of disease following implementation of treatment is recommended (over 1 year of age);

Oseltamivir 5 days
≤ 15kg: 30 mg / dose, two doses per day;
15-23 kg: 45 mg / dose, two doses per day;
23 -40 kg: 60 mg / dose, two doses per day;
40 kg : 75 mg /doz, günde 2 doz;" onmouseover="this.style.backgroundColor='#ebeff9'" onmouseout="this.style.backgroundColor='#fff'">> 40 kg: 75 mg / dose, two doses per day;

Prophylaxis
H1N1 is considered to be in contact with patients to implement recommended (over 1 year of age);

Oseltamivir 10 days
≤ 15kg: 30 mg / dose, single dose;
15-23 kg: 45 mg / dose, single dose;
23 -40 kg: 60 mg / dose, single dose;
40 kg : 75 mg /doz, tek doz;" onmouseover="this.style.backgroundColor='#ebeff9'" onmouseout="this.style.backgroundColor='#fff'">> 40 kg: 75 mg / dose, single dose;

After treatment (10 days later) is applied to the vaccination program.

Oseltamivir in patients younger than one application, dated September 2009 was included in the CDC reported. Pandemic and serious infections have been reported can be applied. Are attached in the literature.